The Indian rupee today depreciated by 3 paise to 44.52 a dollar as the US currency gained overseas.
The rupee had closed 3 paise lower at 44.55/56 a dollar in the previous session.
Marketmen said fresh capital outflows from equities by foreign funds also weighed on the rupee sentiment.
Meanwhile, the Bombay Stock Exchange index Sensex fell by 59.50 points, or 0.34 per cent, to 17,422.53 points in early trade.