Surging global infections of the Omicron coronavirus variant have sparked worries in financial markets as many European nations and Britain weigh the possibility of restrictions during Christmas.
That's definitely a cause of concern," said Chris Zaccarelli, chief investment officer at Independent Advisor Alliance.
Technology, communication services and consumer discretionary, sectors which house majority of the mega-cap growth stocks, extended their slide from the previous session.
Goldman Sachs trimmed its quarterly U.S. GDP forecasts for 2022 after Manchin's comments.
The developments come at a time when the Federal Reserve decided last week to end its pandemic-era stimulus faster, with the central bank signaling at least three quarter-percentage-point interest rate hikes by the end of 2022.
"You have to believe that if the stimulus does not go through because they can't get Senator Manchin's support, and Omicron wreaks some havoc with the economy, then clearly the Fed is going to have to slow down their plans to raise rates," Zaccarelli said.
At 9:49 a.m. ET the Dow Jones Industrial Average was down 600.91 points, or 1.70%, at 34,764.53, the S&P 500 was down 68.96 points, or 1.49%, at 4,551.68 and the Nasdaq Composite was down 228.46 points, or 1.51%, at 14,941.22.
Oracle Corp slipped 3% after the enterprise software maker said it would buy electronic medical records company Cerner Corp for $28.3 billion.
Declining issues outnumbered advancers for a 8.39-to-1 ratio on the NYSE and for a 5.84-to-1 ratio on the Nasdaq.
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