England look on the verge of defeat after India set them a 319 target to win and also gave a superb performance with the ball on the fourth day of their second Test at Lord's.
England lost three wickets for two runs to the visitors including struggling captain Alastair Cook for 22, to end the day on 105-4.
Earlier Murali Vijay hit 95, Ravindra Jadeja 68 off 57 balls and Bhuvneshwar Kumar 52 to help India progress quickly from their overnight 169-4 to 342 all out, The BBC reported.
If England loses on Monday they would be 1-0 down in the series with three matches left to play and extend their winless run to 10 Tests.
After three wickets in the morning session had reduced India to 235-7, Jadeja performed splendidly with the bat to smash against James Anderson and Stuart Broad in a counter-attacking eighth-wicket stand of 99 with Kumar in 16.3 overs either side of lunch.
Late in the day, after the inspired Jadeja had dismissed Sam Robson with his first delivery, Cook and Gary Ballance steered England to 70-1.
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But their 58-run partnership soon ended as Ballance nicked Mohammed Shami behind, and the out-of-form Ian Bell played inside a ball from Ishant Sharma that held its line down the slope and was bowled.
Cook lasted 93 balls of mostly dogged defence before he was tempted into playing at a ball from Sharma and edged to wicketkeeper Mahendra Dhoni. It extended the skipper's run without a century to 27 innings and left England staring at defeat.
On a pitch taking spin, Moeen Ali survived a dropped catch and two huge lbw shouts to finish 15 not out, alongside Joe Root, who has 14. England will bat on Monday, the final day, to try and win the match with Ali and Root facing the Indian spinners.