Joe Biden believes he could have won the Presidency in 2016, had he made it through a tough Democratic primary.
"At the end of the day, I just couldn't do it. So I don't regret not running. Do I regret not being president? Yes," he said.
"I don't regret not running in the sense that it was the right decision for my boy, for me, for my family at the time," Biden added.
The former Delaware senator was speaking to a student audience at Colgate University in central New York state on Friday, reports The Guardian.
Former United States president Barack Obama's vice-president also hopes current President Donald Trump, who has had a controversial run at office in his first two months, "grows into the job a little bit".
"I don't have a lot of hope now," Biden said. "I hope that he succeeds."
In October 2015, after much press speculation and an organised attempt among activists to draft Biden, the vice-president announced that he would not run for the White House for a third time, after short runs in 1988 and 2008.