The market kick-started the week in red. Sensex traded down 94.31 points or 0.4 percent at 25424.91 and the Nifty is down 16.30 points or 0.2 percent at 7745.65.
Sun Pharma is down six percent followed by Infosys, Wipro, HUL and Reliance among major losers in the Sensex.
The top gainers are Hindalco, Tata Motors, Bharti Airtel, Hero MotoCorp and Lupin.
The Indian rupee opened marginally higher by five paise at 66.35 per dollar versus 66.40 Friday.
Experts believe that the Fed hike was well received with all markets rallying initially. However, the continued weakness in energy and oil prices has started to put pressure back on the market.
Brent crude prices fell to their lowest since 2004 on renewed worries over a global oil glut, with production around the world remaining at or near record highs and new supplies looming from Iran and the United States.