Brit-Indian honeymoon murder-suspect Shrien Dewani has lost his latest appeal to block extradition to South Africa.
The 33-year-old is fighting a return to South Africa to face the charges over the death of his wife Anni in November 2010.
Shrien, who has denied murdering his wife, has been given a 28-day period to be extradited.
According to the BBC, Dewani's legal team had wanted the appeal to be heard in the Supreme Court, but was refused by a panel of judges.
Dewani's lawyer told Lord Chief Justice Lord Thomas and two other judges at the High Court in London that his 'underlying medical condition' may have become chronic, making it 'untreatable,' the report added.
The legal battle to keep Dewani in England until he is well enough to travel has been ongoing since 2011.