Eman Ahmed, who was once titled as 'the world's heaviest woman', passed away in Abu Dhabi on Monday in Burjeel Hospital.
She died just a week after celebrating her 37th birthday.
Hospital officials said that numerous co-morbid conditions including heart diseases and kidney dysfunction resulted in her death.
Earlier in February this year, Eman, was brought to Mumbai's Saifee Hospital for weight-loss treatment and transferred to Burjeel Hospital on May 4 after spending three months in Mumbai. She weighed 504kg when she arrived in Mumbai on February 11.
She was a resident of Alexandria, Egypt.