At closing bell, the benchmark Hang Seng Index declined 0.91%, or 215.19 points, to 23,420.76. The Hang Seng China Enterprises Index dropped 0.9%, or 75.70 points, to 8,342.91.
The US Treasury Department sanctioned eight companies, including drone maker DJI Technology and artificial intelligence giant Megvii. The Commerce Department separately added 34 firms to its so-called entity list.
Among major decliners, Tencent and Alibaba Group Holding lost more than 3.1%, while Meituan retreated 5.3%. Xinyi Solar, which produces solar panels in Xinjiang, sank 9.4% while Xinyi Glass tumbled 6%.
On the up side, HSBC climbed 2.8% while Standard Chartered jumped 2.3% after a surprise rate increase by the Bank of England, a move that could improve interest margins on their lending in home markets.
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