At closing bell, the benchmark Hang Seng Index fell 1.21%, or 311.58 points, to 25,502.23. The Hang Seng China Enterprises Index dropped 1.7%, or 157.26 points, to 9,081.73.
Shares of Alibaba Health Information Technology and Country Garden Holdings slumped by at least 5.3%, among the market's worst performers. Countering losses, PetroChina advanced 3.9% after crude oil topped US$70 a barrel, as a storm approaching the Gulf of Mexico clouded supply outlook.
Shares of property developers declined, with China Evergrande Group, the country's most-indebted developer, plunged nearly 12% to its lowest in more than six years, after it warned of a risk of cross-default as real estate sales continued to plunge.
Shares of China Evergrande New Energy Vehicle and Evergrande Property Services, units that Evergrande has been attempting to sell, also plummeted 24.7% and 12% respectively.
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