Classes have been suspended at university campuses around Mexico to protest against the government's failure to locate the 43 college students who went missing in September.
Students and faculty in Mexico City, Michoacan and Oaxaca have gone on strike, reported Xinhua.
"More than 65,000 students from the San Nicolas de Hidalgo University of Michoacan began a 72-hour strike in support of the 43 teaching students who disappeared," the daily La Jornada said.
Classes were suspended at 51 university campuses in and around Mexico City, including the schools of medicine, dentistry, psychology and law at the National Autonomous University of Mexico.
On Thursday, students and teachers are set to march in Mexico City from the presidential palace of Los Pinos to the central square, and Friday, protesters plan to "seize" toll booths on federal highways.
The protests come a day after federal authorities detained fugitive mayor of Guerrero town of Iguala, Jose Luis Abarca, and his wife, who were believed to have ordered an attack that killed six people and left the 43 students missing.