At least four people were killed and 40 others wounded in the Egyptian capital and other parts of the country Friday during protests staged by supporters of ousted president Mohamed Morsi, Al Jazeera reported.
Morsi's loyalists clashed with police when they attempted to enter Tahrir Square in Cairo. Eyewitnesses said that tear gas shells were fired to disperse protesters.
In Alexandria, too, police fired tear gas to dissuade local residents from fighting with anti-coup protesters.
Another report said that an army vehicle fired live rounds in the direction of Brotherhood supporters in the national capital.
The protesters chanted slogans "down down with the murderer" - a reference to army chief General Abdel-Fatah el-Sissi, who forced Morsi out of power in July this year.
Footage of state TV showed that hundreds of protesters coming out of main mosques after the Friday prayers carried banners with pictures of victims in a crackdown on Morsi's supporters Aug 14, vowing to take revenge.
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Across the country, similar clashes broke out with police firing tear gas and gunshots in the air as residents and protesters clashed and threw stones at each other.
The National Alliance for Supporting Legitimacy, whose members mainly come from the Muslim Brotherhood, has called for continuous protests in Tahrir Square from Friday.