The Librarian government on Friday confirmed a new Ebola case traced to a 30-year-old woman.
The ministry of health in a statement asked the citizens not to panic in the wake of the new Ebola case, according to to Xinhua.
The woman was taken to the Redemption Hospital on Thursday evening, and died on arrival, the statement said in the capital Monrovia.
Her blood specimens were taken and tested positive of Ebola.
This latest pronouncement by the ministry comes more than two months after the haemorrhagic virus that killed more 4,800 was declared over in the country.
A health official told Xinhua that the recurrence is a setback to the progress made in curtailing the virus in the West African nation.
A resurgence of Ebola in Guinea has killed seven people in the last few weeks, but it is not known if the Liberian case is linked.
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The recent announcement of Ebola in Guinea prompted the Liberian government to close its border with Guinea.
The World Health Organisation reported Ebola symptoms in Guinea on March 16 while at the same time it made reference to another case in neighbouring Sierra Leone.
Liberia was one of three countries in the West African sub-region worst hit by the outbreak with 4,800 deaths.
The WHO in a statement said that the Ebola outbreak in West Africa no longer constituted an international emergency, voicing confidence that remaining isolated cases in the affected countries can be contained.