Anuradha Shandil, 57, died in the All India Institute of Medical Sciences, where she was hospitalised for quite time, the family said.
She was working with the Jawaharlal Nehru University in Delhi as the chief medical officer.
Chief Minister Virbhadra Singh and Governor Urmila Singh mourned her demise.
Shandil is a two-time former Lok Sabha member and first-time legislator from Solan.