Local favourite John Isner breezed past Kevin Anderson 6-3, 6-4 to open his Western & Southern Open campaign.
The two had met nine times before Monday and eight of them had at least one tie-breaker. However, Isner put in a dominating performance and cruised into the next round with a straight sets win, reports Xinhua.
Isner, the highest-ranked US male player, was the runner-up in last year's tournament.