Hasan Rouhani's remarks about Israel his country's archenemy echo those of other Iranian leaders.
Iran's semi-official ISNA news agency says Rouhani spoke after taking part in an annual pro-Palestine rally in Tehran today.
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The report quoted Rouhani as saying: "The Zionist regime has been a wound on the body of the Islamic world for years and the wound should be removed."
Rouhani won a landslide victory in Iran's June 14 presidential election. He replaces Mahmoud Ahmadinejad on Sunday.
Rouhani has pledged to follow a "path of moderation" and promised greater openness over Iran's nuclear program, which has placed it at odds with the West.