Sixteen people including political activists and a senior police official have been killed in the city since Monday, while unidentified gunmen wounded a civil judge yesterday.
Police said that 10 people were killed and at least nine others were injured, including four in the posh shopping area of Tariq road, in firing incidents yesterday.
The fresh wave of violence started last week and police said in many incidents assailants targeted political activists of different parties.
Imran Baig a political activist was shot dead in Shah Faisal colony and the incident sparked chaos and panic in the locality and normal business activity was suspended.
Mehdi Raza and Ahmer Raza were killed by unidentified armed assailants in Orangi Town number 10 near Aslam Shaheed Roundabout.
Many of the political activists killed since last week belong to the Mutthaida Qaumi Movement and Pakistan People's Party.