The militants were killed in a operation launched in the Panjgur district, Khan Wasey, a Frontier Corps (FC) spokesman told reporters.
"These militants were involved in target killings, bomb attacks and kidnappings," he said.
"Three FC soldiers were also critically wounded in the operation carried out in the mountainous region of Panjgur," he added.
Three militant hideouts and two vehicles were also destroyed.
A FC source said that the militants belonged to a banned Baluch separatist outfit.
Balochistan has seen an upswing in violence recently, suffering from a separatist insurgency, sectarian violence and Taliban militants.