Averaged across men and women, the US -- at 78.8 years -- was 27th in life expectancy at birth among the 34 countries in the Organisation for Economic Co-operation and Development, the intergovernmental organisation said.
Forty years ago, Americans lived a year longer than the OECD average, but today they have fallen well below the median, it said.
At the same time, the US outstripped other nations in per capita health expenditure, spending two-and-a-half times more than the average within the ODED, which also includes a handful of emerging economies such as Mexico and Turkey.
Average lifespan across all OECD nations reached 80.5 years in 2013, an increase of more than 10 years since 1970.
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A persistent gap in life expectancy between women, who live longer, and men has gradually narrowed from about seven years to five, the study found.
Japan -- at 83.4 years -- along with Switzerland and Spain topped the charts for life expectancy in 2013, followed by Italy, France and Australia, according to the annual overview of health metrics.
Several factors account for the poor and declining life expectancy in the US, the report said, starting with its weak public health sector and the millions of Americans who remain uninsured.
High income inequality, illegal drug use, along with high rates of obesity, traffic accidents and homicide also push average life spans down.
Looking at major risk factors -- smoking, alcohol and obesity -- the US ranked last on the obesity index, but was among healthiest nations for tobacco consumption.
Sweden and Norway were the only countries among the 34 in which all three risk factors remained very low.