The incident happened around midnight in the centre of the city, with six males and five females receiving minor injuries, government and police officials said. Some of the victims were taken to hospital.
It is not clear what caused the accident. The South China Morning Post reported the driver of the westbound tram may have lost control of the vehicle.
Trams, known as "ding-dings" for the sound of their bells, have serviced the city's main island for more than a century and carry around 200,000 passengers a day.
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