While ten persons died on the spot, another succumbed to injuries on way to hospital. The deceased include four women, SP (City) Ashok Kumar said.
The condition of three of the injured is serious.
The accident occurred when an auto carrying 15 passengers tried to overtake a bus and collided head-on with a college bus coming from the opposite direction.
The auto was going to Mathura from Vrindavan when the mishap took place.