Army spokesperson Brigadier Gen Mohamed Samir said that the army killed the militants and arrested 51 terrorists.
He said in a statement that a soldier was killed and another was injured after a bomb exploded during the raids.
Five vehicles were also destroyed during the campaign.
Egyptian army recently started a major campaign in the cities of Rafah, Sheikh Zwayed and Al-Arish against militants.
The North Sinai region has witnessed many violent attacks by militants since the January 2011 revolution that toppled the president Hosni Mubarak.
More than 600 security personnel have been reported killed since then.
The military has launched security campaigns in the area, arrested suspects and demolished houses that belong to terrorists, including those facilitating tunnels leading to the Gaza Strip.