The 12 militants at Nasau area in Kohli district of the southwestern province were killed in an exchange of fire during a targeted operation by Frontier Corps and security forces, a senior official said.
Two commanders of banned Balochistan Liberation Army, Jamir and Baloch Khan, were also killed in the search operation, The Express Tribune reported.
A large cache of arms and ammunition was recovered from their possession.
The militants were involved in previous attacks on security forces, targeted killings and other terrorist activities.