In Hunan, continuous rain resulted in swollen rivers, landslides and mud-rock flows.
Three people died in Hengshan county, according to the provincial flood control and drought relief headquarters.
Three residents of Xiangtan County have been reported missing after their home was buried by a landslide today, while in Longhui county one person was reported missing.
About 530 houses collapsed, and 11,900 people were evacuated, said the headquarters.
In Guangxi, one person was killed by collapsing house in torrential rain, said the regional civil affairs department.
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In Jinping County in Guizhou, five people have died and four are still missing, according to the county's information office.
Heavy rain pounded the county from last night until early today, with 202 millimeters of precipitation recorded in some areas.
Traffic, power and telecommunications were all affected and homes destroyed.
Around 10,000 residents of 24 counties in Guizhou have been displaced.
The homes of 125 families have been destroyed and 300 more have been seriously damaged, said a statement from the provincial civil affairs department.
Nearly 300 rescuers are searching for the missing around the mountain, which experienced heavy torrential rain.