The accident occured when the bus collided with the truck on Khushab road in Jhang district, killing 13 people.
Rescue teams arrived at the scene and shifted the dead and injured to different hospitals.
Punjab Chief Minister Shahbaz Sharif expressed deep sorrow and grief over the loss of lives and directed officials to provide all medical care to the injured.
Road accidents are common in Pakistan and most of them are caused by rash driving and bad roads.