Reconstructive surgery on the human nose is not uncommon, but until now, doctors in the US had not been able to replicate and restore the body part to its full functionality.
Dallan Jennet, a 14-year-old boy from the Marshall Islands, a country that lies near the equator in the Pacific Ocean, is the first patient in the US to undergo a procedure that did just that, Fox News reported.
"The procedure is akin to a 'nose transplant' in that we were able to replace the nose with a functional implant," lead physician Tal Dagan, associate adjunct surgeon, said in a Mount Sinai blog post.
"This procedure may be a breakthrough in facial reconstruction because the patient will never have to deal with the standard issues of transplantation, such as tissue rejection or a lifetime of immunosuppressive therapies," he said.
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Benicia, California-based nonprofit Canvasback Missions Inc, an organisation that provides health care and health education to the Pacific Islands, funded Jennet and his mother's travel and medical expenses to New York.
To carry out the subsequent surgeries, Dagan and Dr Grigoriy Mashkevich, assistant professor of Otolaryngology, Division of Facial Plastic and Reconstructive Surgery at Mount Sinai, collaborated with Oxford Performance Materials Inc, a Windsor, Connecticut-based 3-D printing company.
The team created Jennet's 3-D nose graft by replicating the structure of his family's noses.
They then harvested blood vessels and tissues from the boy's thigh, removed excess scar tissue, inserted the graft, and reconstructed the skin over the 3-D implant. They carried out four more surgeries, and Jennet attended follow-up appointments between June and October.
The surgeries were successful, and doctors said the 3-D printed implant will grow with him -- preventing the need for additional reconstructive procedures.