Acting on a tip-off, rural police apprehended the four smugglers when they were making arrangements to transport the contraband weighing 168kg in a van at Pallavuru under KD Peta Police Station limits, said Circle Inspector R Mallikarjuna Rao.
The arrested were identified as Reddy Narasimha Murthy (28), Singampalli Sattibabu (50), Datla Ramaraju (56), all native of Visakhapatnam district, and D Sandeep Kumar Khatik (28), a resident of Bhopal.
Murthy and Sattibabu were earlier, too, involved in ganja smuggling cases, Rao said.
The Inspector said the four-member gang had procured the ganja from parts of Chintapalle and stored at Pallavuru.