The incident occurred as some people were watching a football match sitting on the eaves of the under-construction building which collapsed.
Chando Baskey (55) of Ambajora village and Sushil Marandi (35), a resident of Kolha Badar village were killed on the spot, the police said.
The injured persons, Rajan Jadopatiya and Manik Hansda, were admitted to Maulpahari Hospital.
The football match was organised on the occasion of 'Hul Diwas' (Revolution day) at Shaikaripada College ground.