The chopper crashed in an open ground in Dagang Township, Nansha District of the provincial capital city of Guangzhou, state-run Xinhua news agency quoted local officials as saying.
The two people aboard the helicopter, a 37-year-old male pilot surnamed Pan and a 25-year-old female trainee pilot surnamed Xi died on the spot.
The two were engaged in a training course at the time of the accident.
The helicopter belonged to a general aviation company based in Guangzhou.