A high court late yesterday ordered the two men to be hanged.
Prosecutors say Dennis Williams and Royden Williams were part of a group that went to the jungle community of Bartica to steal from gold miners and wound up killing the 12 people.
Police say the men also were part of a gang also linked to a separate killing of six adults and five children just months earlier.
Several inmates remain on death row in Guyana, although the country hasn't hanged a prisoner since 1997.
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