"Never in recent memory have so many children been subjected to such unspeakable brutality," UNICEF director Anthony Lake said yesterday.
"Children have been killed while studying in the classroom and while sleeping in their beds; they have been orphaned, kidnapped, tortured, recruited, raped and even sold as slaves."
"This has been a devastating year for millions of children," he said.
Globally, 230 million children currently live in countries and areas engulfed in violent conflict, according to UNICEF.
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More than 7.3 million children are affected by the war in Syria and 2.7 million in Iraq.
In Gaza, 54,000 children remain homeless from the 50-day war between Israel and Hamas militants that ended in August. Of the more than 2,000 dead from the fighting, 538 were children.
Up to 10,000 children have been recruited by armed groups in the Central African Republic over the past year and more than 430 children have been killed and maimed -- three times as many as last year.
South Sudan armed forces and groups have recruited around 12,000 child soldiers this year, according to UNICEF.
The world's worst outbreak of Ebola has left thousands of children orphaned while some 5 million are out of school in the three hardest-hit countries: Guinea, Liberia and Sierra Leone.
"The sheer number of crises in 2014 meant that many were quickly forgotten or captured little attention," UNICEF said citing ongoing violence in Afghanistan, the Democratic Republic of Congo, Nigeria, Pakistan, Somalia, Sudan and Yemen.