We have detained 22 persons apprehending that they might breach security during today's VVIP visit," Senior Superintendent of Police (SSP) Deepak Kumar said.
Those detained included some youth leaders belonging to the Samajwadi Party (SP).
Earlier during a visit by the Uttar Pradesh Chief Minister Yogi Adityanath to the Lucknow University on June 7, a number of students had blocked his cavalcade, raised slogans and waved black flags.
The police had a tough time in controlling the protesters.
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Last year in January, when Prime Minister Modi visited the Dr Bhim Rao Ambedkar University here, he too was greeted with protests as soon as he began speaking at the event.
The protesting students were, however, made to leave the auditorium.
The security agencies have tried to make fool proof arrangements this time during the PM's two-day visit to the city.