The fire broke out due to boiler explosion at the four-storey Tempako Packaging Factory around 6:15 AM in Bisic industrial area of Tongi, north of Dhaka, said Gazipur Fire Service and Civil Defence Deputy Assistant Director Akhtaruzzaman.
A part of the building collapsed as the rage of the blaze spread despite frantic efforts of the fire fighters.
At least 26 people were killed and than 74 others sustained burn injuries, hospitals sources said.
While 30 burnt victims were rushed to Dhaka Medical College Hospital, 10 others shifted to Kurmitola Hospital, said the residential physician.
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Ten of the injured are struggling for life with critical burn wounds, officials said.
Twenty five units of firefighters were trying to douse the fire.
Flames and smoke were seen billowing out of the factory, six hours after the fire started. The fire service said strong winds had fanned the flames.
The factory produced and printed the plastic packaging for food items like potato chips and small household goods including mosquito coils.
Low-cost manufacturing is a mainstay of Bangladesh's economy, but a series of industrial disasters in recent years have raised concerns about safety standards.
Tighter controls have been introduced, but dozens of workers still die every year.
At least 13 people died in a fire at a plastics factory Dhaka last year.
In 2012, 112 workers died in a fire at a factory just outside the capital.
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