The accident took place on Jabalpur-Jaipur National Highway in Narsinghgarh sub-division of the district when the Bhopal-bound bus coming from Kota hit the jeep, killing three of its occupants on the spot, inspector Ranjit Singh Parmar said.
The deceased were identified as Dilshad Khan, Nitin Sharma and Rahul Sharma, he said.
Among the 15 injured, who were travelling in the bus, the condition of two persons was stated to be serious and they were referred to Bhopal, he said.
A case has been registered in this regard against the bus driver and further probe is on, police added.