A Pakistani security official confirmed the death of three persons in the strike on a house in Mir Ali area of North Waziristan Agency.
The attack came a day after the Advisor to the Prime Minister on Foreign Affairs and National Security Sartaj Aziz told Pakistan's National Assembly that the government will take up the issue of drone strikes with the US in September.
The US has not stopped its drone campaign despite repeated protests from Pakistan, which describes the attacks as violation of its sovereignty and counter-productive for the war on terror.