The incident took place at about 3 pm on Sunday near Chahel Dhaba on the Muktainagar-Varangaon road on National Highway Number 6.
According to the Muktainagar police, an unidentified truck driver rammed into a motorbike killing the biker alongwith a pillion rider on the spot.
After hitting the bike, the out of control truck also rammed unto a truck, injuring its driver Mahadeo Laxnan Morle (35), a resident of Nagpur.
Morle is said to be very critical and undergoing treatment at Jalgaon civil hospital, the police said.