Police Maj Gen Suwit Choensiri says the men used blades to cut the cell's bars and used ropes made of clothes to escape from the Sadao district police station in Songkhla province early today.
He says police are checking closed circuit television footage to trace the men.
More than 1,700 asylum seekers from Myanmar's beleaguered Rohingya minority who arrived in Thailand by boat early this year are being held in crowded detention centers.