The 8,848-metre-high peak has attracted climbers from more than 40 countries this season.
Around 300 climbers including youngest Mathew Momiz, 16 and oldest William Mithcell Burkey, 73, from the US and women climbers Deerness Joy Christine, 65, from New Zealand and Azer Alyssa Nicole, 18, from Australia have recently moved towards the base camp in the Everest region.
According to officials at the Mountaineering division at the Ministry of Tourism and Civil Aviation, this season 75 expeditions have got permission to climb mountains and 28 of them got permission to scale the world's highest peak.
Each climber will have to bring back eight kg garbage in addition to their own from the top of the Everest as per the latest regulation introduced by the government to keep Everest region clean.
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It is estimated that around 2.4 metric tonnes of garbage will be collected from Everest in this spring.
"There is no excuse and it doesn't matter who they are, where they are from, as a climber everybody is required to submit the rubbish at the Base Camp," Madhusudan Burlakoti, spokesperson at the Tourism Ministry said.
A contact office with at least nine staffers will be established at the base camp in the first week of May, according to officials.
Security personnel, ministry officials and support staff have reached the camp to facilitate climbers.
According to trekking entrepreneur Nima Nuru Sherpa, icefall doctors have already installed ropes up to Camp 2.
Climbers are now acclimatising in the Khumbu region and expedition support staff are preparing the way by setting up camps, tents, food supply and other equipment.
Until last year, there were 6,871 summits- 4,416 from Nepal side and the rest from Tibet side.
So far 3,500 people have reached the top of the world since 1953, when the first summit was made by Tenzing Sherpa and Edmund Hillary.
In 2013, 539 summits were recorded from Nepal side, while Tibet side recorded 119 summits.
Since the Everest was opened in 1953 there were 248 casualties, including 161 of foreigners, according to officials.