West Yorkshire Police launched a murder investigation following the discovery of four bodies at the detached property in the Clayton area of Bradford.
"Police were called to the house last night following concerns from a neighbour, who had not seen the family for some time," a West Yorkshire Police statement said.
Inside the property, police found the bodies of two adults -- Jatindra Lad, 49, and his wife Duksha Lad, 44.
The bodies of their teenage daughters, Trisha, 19, and Nisha, 17, were also found in the house.
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Detective Superintendent Simon Atkinson of West Yorkshire Police said: "This is clearly a significant incident and our investigation will be thorough as we piece together the events that have led to the deaths of a local family."
"The investigation is at an early stage and while I do not want to speculate around the circumstances leading to the deaths, I am happy to confirm that we are not looking for anyone else in connection with this incident," he said.
"Additional neighbourhood officers are in the area speaking to people and offering reassurance," he said.
The family had lived in the "peaceful" village for at least 20 years.
A white car was parked on the driveway of the detached two-storey house that was sealed off with police tape for a forensic investigation.
Sehaj Singh, 19, said he had known the older daughter for eight years and added she was in her second year at Leeds University.
Describing her as a quiet girl, Singh was quoted as saying: "She was really nice. She was just one of those people who got on with things."
Jessica Garside, 18, who went to nearby Thornton grammar school with the older girl, said of her friend: "She was a lovely person. Never said anything bad about anybody.