The most prominent among those defeated in the elections was Excise Minister K Babu, who was under a cloud of charges in the bar bribery scam which shook the Congress-led UDF government.
He was defeated by CPI(M)'s firebrand debutant M Swaraj in Thrippunithura segment by a margin of 4,467 votes.
Other ministers who were defeated included P K Jayalakshmi, the lone woman minister in the Chandy cabinet, JD(U) leader and agricultural minister K P Mohanan and RSP leader and Labour minister Shibu Baby John.