An official of the National Institute of Health in the capital confirmed the cases, saying three cases reported from Qilla Abdullah and Quetta in Balochistan and one from South Waziristan tribal region along Afghan border.
The victims never received anti-polio vaccine due to refusal of their parents. Pakistan has already broken its 14-year old record of 199 polio cases in one year that was recorded in 2000.
So far 151 cases have been reported from tribal areas, 48 from Khyber-Pakhyunkhwa province, 23 from Sindh, 10 from Balochistan and three from the largest province of Punjab.
Pakistan government has come under criticism for doing little to eradicate the virus which is a threat to the world.
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Security is the main reason for the spread of polio virus as vaccination cannot be organised in tribal areas where Taliban still control large areas.
They consider polio medicine as a conspiracy by the West to sterile Muslims. Peshawar is considered as hub of poliovirus.