State and national emergency officials said they had no immediate reports of damage from the latest shake, but schools were cancelled across the state on Monday.
It was felt in Mexico City, where quake alarm sirens had people springing out of their beds and into the streets.
The US Geological Survey said the quake hit at 12:57 am (0657 GMT). It was centered 25 miles (40 kilometers) beneath the surface at a point 33 miles (54 kilometers) east-northeast of Pinotepa Nacional and 69 miles (111 kilometers) southwest of the state capital, Oaxaca city.
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