Timothy Ray Jones Jr, 32, led investigators to the site where the bodies of the children were found, off a two-lane highway near Camden, Alabama, said Alabama Department of Public Safety spokesman Sgt Steve Jarrett yesterday.
Jones has been charged with child neglect and police expect to lodge additional charges against him in connection with the children's deaths, authorities in South Carolina and Mississippi said.
"This is a very tragic situation," Jackson said. "These kids' lives were snuffed out before they had a chance to enjoy life. Justice will be served."
Police have not released details on how the children died. Lexington County Coroner Earl Wells was arranging for the children's bodies to be taken back to South Carolina for autopsies and identification Tuesday night, sheriff's officials said.
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Jones was detained in Smith County on Saturday after being stopped at a motor vehicle checkpoint near Raleigh, Mississippi, and charged with drunken driving, Smith County Sheriff Charlie Crumpton said in a news release.
Crumpton said Jones became agitated when a deputy questioned him about an odor of chemicals coming from the Cadillac Escalade he was driving.
The deputy found what were believed to be chemicals used to manufacture methamphetamine and a substance believed to be the street drug Spice, a form of synthetic marijuana, Crumpton said.
During a background check, police discovered that Jones was wanted in South Carolina "regarding a welfare concern of his children," who were on a national missing persons list, the Mississippi Bureau of Investigation said in a statement.
Investigators from several departments and the FBI started looking for the missing children on Monday, Crumpton said.