The Jackson County Sheriff's Office confirmed the deaths yesterday afternoon. The names of the children haven't been released.
Emergency personnel arrived shortly after 5 am (local time). Yesterday, at the home in Edna, 160 km southwest of Houston.
Sheriff A J Louderback says the children's parents were found outside the home with one child but told firefighters five children were still inside. The home was engulfed in flames when authorities arrived.
Edna Fire Department Capt Nick Strauss says firefighters weren't able to make rescue attempts due to the roof collapse.