The accident occurred near Thikaria area on the highway due to dense fog in the morning, police said.
The roadways bus collided with the tanker, leading to a pile-up involving total seven vehicles, said Poonam Chand, Circle Officer of Police of Manpur.
The five injured were admitted to a local hospital where they were administered first-aid.
"A gas tanker was damaged. However, no leakage occurred," he said.
Meanwhile, dense fog in northern region disrupted train services on routes under North Western Railway (NWR).
Twenty trains were running late by up to 17 hours 50 minutes, according to an NWR spokesperson.