"The accident took place on Bhavnagar-Dholera state highway when the SUV collided head-on with a truck," an official from Velavadar-Bhal police station said, adding the victims were on their way to Bhavnagar from Mumbai.
Five persons travelling in the SUV were died on the spot, he said, adding four of them were of the same family.
The two injured children, both below five years of age, were rushed to a hospital, police said.