The mishap occurred at Hyrige village, about 40 km from here on the Mysore-H D Kote Road, and the driver abandoned the car and fled the scene along with another person, police said.
Four women died on the spot while another succumbed to her grievous injuries at a hospital, police said.
The deceased were working at a private garments factory, a unit of the Skills Empowerment in Apparel Manufacturing (SEAM) in Belawadi on the city outskirts.
Villagers, who gathered in large numbers at the accident spot, found empty liquor bottles in the car, police said.
District In-Charge Minister S A Ramdas has announced Rs one lakh compensation each to the families of the deceased.