The blast took place in Cairo's Al-Haram district ahead of Monday's anniversary of the 2011 revolution that ousted former strongman Hosni Mubarak.
Six people were killed when a blast took place after a team of security personnel attacked a militant hideout in Giza area here. The area was cordoned off by the security forces after the explosion.
Earlier today, at least five Egyptian policemen were killed when militants stormed a police checkpoint in the country's restive North Sinai and opened fire on them.
The attacks targeting police and military further increased after the ouster of Islamist ex-president Mohammed Morsi in 2013 following massive protests.