According to the report by Sindh Police, 15 officers were killed in September, 12 in October, 11 in November, 11 in December, 25 in January and five so far in February.
In all, police lost 79 officers since the start of targeted operations against militants and criminals in September.
Police also arrested 15,671 suspects. A total of 804 gun battles and 10,254 raids have been recorded till now, the report said.
The targeted operations were started on the orders of the provincial government after a visit by Prime Minister Nawaz Sharif to Karachi to deal with the deteriorating law and order situation in the business hub.