Though the impact of the strike by the United Democratic Madhesi Front (UDMF) has been minimal in the Kathmandu Valley, educational institutions remained shut.
Markets remained by and large open in the Kathmandu Valley and traffic was near normal.
Police have arrested 85 people here for trying to enforce the strike. Security was stepped up in view of the protest.
No incidents of demonstration were reported, police said.
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Chief District Officer Baldev Gautam said the police resorted to firing after they failed to control the Madhesis. They earlier baton charged them and fired tear gas shells.
The UDMF has demanded that the victims be declared martyrs and compensation be given to their families.
Madhesis have been staging protests by burning tyres at various parts of the Birgunj in Parsa districts as well.
A large number of security personnel have been deployed to prevent any untoward incidents in the region.
The protest had resulted in the death of at least 50 people.