A barrage of raids hit Al-Bab yesterday, killing 72 civilians including 21 children, according to the Syrian Observatory for Human Rights.
Bombardment continued today, leaving another 16 civilians dead, including three children.
"Eighty-eight civilians have been killed in 24 hours," Observatory head Rami Abdel Rahman told AFP.
He said it was the bloodiest attack by Turkish forces that his monitoring group had recorded since Ankara began its intervention in Syria in late August.
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Turkish forces and their Syrian rebel allies have been seeking to capture Al-Bab, about 25 kilometres from the northern Syrian border, for weeks.
IS yesterday released a video purportedly showing two captured Turkish soldiers being burned alive, after Ankara vowed to respond to 16 of its troops being killed in the fight against the jihadist group.
Turkish troops entered Syria on August 24 in support of pro-Ankara Syrian rebels, with the aim of ousting IS jihadists as well as Kurdish militia from the border area.
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